Joint pain can occur when the soft tissues that support the joint become damaged, either through injury, or everyday wear and tear.

Repetitive motion/strain damages the slippery cartilage that caps bones in a joint. As the damage increases, bare areas of bone may be exposed. When unprotected bone surfaces rub together, pain and stiffness result. Both the damage to the cartilage and the impact on the bones can establish inflammation, which can cause pain, stiffness and additional impairment to increase. Among the agents of inflammation in this process are a cartilage-degrading enzyme known as matrix metalloproteinase-3 (MMP3), and a pro-inflammatory signal molecule known as 5-lipoxygenase.

Collagen is one of the main components in the soft tissues, such as cartilage, that protects and support joints. Collagen is a protein made from amino-acids including glycine, proline, glutamine, hydroxyproline and arginine.

There are up to 29 different types of collagen that are used in a variety of ways throughout the body, with 4 comprising the most common. The strongest and most abundant is type I, which is found in scar tissue, skin, tendons, artery walls and bones, and makes up over 90% of our collagen.

The qualities of collagen are protected by protein-sugar complexes known as proteoglycans. Aggrecan is one of the most important proteoglycans in cartilage.

Here are more alternatives to Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for better joint health:

  1. BOSWELLIA SERRATA is a botanical supplement made from a tree resin in the same genus as frankincense. It has anti-inflammatory properties.
  2. AVOCADO SOY UNSAPONIFIABLES (ASU) are natural vegetable extracts made from avocado and soybean oils. They contain anti-inflammatory substances (phytosterols).
  3. NATURAL EGGSHELL MEMBRANE (NEM) is derived from the inner and outer layers of the membrane within an eggshell. NEM is a good source of collagen and other nutrients that support the maintenance and repair of soft tissues in a joint.

Summary
New natural products, such as Boswellia serrata extracts, Avocado-Soy Unsaponifiables and Natural Eggshell Membrane, are emerging as alternatives which meet or exceed the benefits provided by glucosamine and chondroitin for joint health and may allow many to reduce or replace their usage of NSAID medications.

Click on each product name in numbered list above for more information.

 

References
https://www.news-medical.net/health/Collagen-Types-and-Linked-Disorders.aspx accessed March 9, 2018
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